Active Pharmaceutical Ingredient (API) is a term that has become increasingly prominent in the pharmaceutical industry. It refers to the biologically active component in a drug that produces the desired therapeutic effect. By understanding APIs, we can gain insight into the intricate processes involved in drug development, manufacturing, and regulation.
Formulation refers to the process of combining APIs with other substances to develop a viable drug product. These additional substances, often referred to as excipients, can include fillers, binders, preservatives, and stabilizers. The formulation is crucial because it determines the drug's stability, absorption, distribution, metabolism, and excretion (ADME) properties.
api and formulation in pharma
Chillers use water to absorb heat from the process or environment and then reject that heat to the atmosphere. This operation creates ideal conditions for scale formation and corrosion, which can result from the water’s mineral content and temperature fluctuations. Without effective treatment, scale can settle on heat exchanger surfaces, diminishing heat transfer efficiency and leading to higher energy costs. Similarly, corrosion can damage metal components, eventually causing leaks and system failures.